Monday, March 8, 2010

Research: Larazati - A Medication For Celiac Disease

A new treatment is being researched for celiac disease that will include an oral medication called Larazati. Clinical trials have just been completed and show promising results. 

The study was being completed to:
evaluate the efficacy of multiple dose levels of  [Larazati] AT-1001 in preventing intestinal permeability changes induced by a 6-week gluten challenge.

The 184 participants remained on a gluten free diet but along with their determined dosage of Larazati (or the placebo) were given a pill that contained 900mg of gluten. The medication was taken orally 15 minutes before each meal (breakfast, lunch and dinner) as well as the gluten capsule. 

The medication is said to strengthen the junctions that hold the intestine together which then blocks the gluten from going into the tissue and damaging it.  The trials have also showed some promise in repairing already damaged tissue. 

The medication is not being hailed as a cure for celiac disease but as another way to help those affected everyday by protecting from those times when they accidentally come into contact with gluten. 

The trials are still ongoing to look further into the safety and dosage.

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